If you were told to ingest a biologically alien synthetic chemical whose presence on this
planet did not predate 1976, and whose structure is only a few atoms away from the deadly
pesticide DDT, and you knew that not only were there no long term human safety studies
performed on it, but that it had been already proven in tests to have following adverse
health effects:

•        Shrunken thymus glands (up to 40% shrinkage) (EO56)
•        Enlarged liver and kidneys. (EO57 & E161)
•        Atrophy of lymph follicles in the spleen and thymus (EO51, EO56, EO151)
•        Increased cecal weight (E151)
•        Reduced growth rate (EO57)
•        Decreased red blood cell count (EO55)
•        Hyperplasia of the pelvis (EO57)
•        Aborted pregnancy (Maternal & Fetal Toxicity) (E134)
•        Decreased fetal body weights and placental weights (EO32)
•        Increase glycosylation of hemoglobin (HbA1c) for diabetics (E157)

[The citations above, e.g.(E....) were studies provided by McNeil Nutritionals, the manufacturer of sucralose, in pre-
approval studies which for obvious reasons they did not publish]

….would you still consume it? Of course not! And yet, millions of Americans (including our
precious children!) are doing exactly that by consuming Splenda.  
So, what is sucralose, chemically speaking?

Like “Splenda,” the term “sucralose” is a cute little marketing ploy. The true name of this
ugly little chemical is actually too long for the human tongue to comfortably pronounce
(which is usually an excellent indication that it is not safe to ingest!) Go ahead and see if you
can wrap your vocal chords around this monstrosity:

1,6-dichloro-1,6-dideoxy-BETA-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-
galactopyranoside


Despite the intended insinuation, sucralose is not a form of sucrose (cane sugar).
Sucralose/Splenda is produced through artificially substituting three hydroxyl groups
(hydrogen + oxygen) with three chlorine atoms in the sugar (sucrose) molecule. Natural
sugar is a hydrocarbon built around 12 carbon atoms. When transformed into Splenda it
becomes a chlorocarbon, in the same family as deadly pesticides like DDT, insecticides,
biocides, disinfectants like Chlorox Bleach, and WWI poison gas like dichlorourea.
The makers of sucralose/Splenda argue that this "remarkably stable" chemical passes
unchanged  into the urine and feces, when in fact, up to 11% to 27% is absorbed into the
body (FDA, 1999).  In fact, the varying degrees to which sucralose is absorbed is used as a
marker for gut and intestinal permeability to determine certain disease states.  Once
absorbed, some portion of this chlorocarbon accumulates in the body (between 1.6% to
12.2%).  What effects will these accumulated chemicals have?  According to James Bowen,
M.D:

"Any chlorocarbons not directly excreted from the body intact can cause immense
damage to the processes of human metabolism and, eventually, our internal organs.
The liver is a detoxification organ which deals with ingested poisons. Chlorocarbons
damage the hepatocytes, the liver's metabolic cells, and destroy them. In test animals
Splenda produced swollen livers, as do all chlorocarbon poisons, and also calcified the
kidneys of test animals in toxicity studies."

How can this be true for an FDA approved sweetener?

FDA approval does not in any way guarantee safety.....sadly enough, in many cases, it
guarantees the exact opposite.  Take aspartame for instance. Aspartame
(Equal/NutraSweet) contains 10% methanol, which is broken down in our body into two
extremely toxic substances: formaldehyde and formic acid.  This sweetener gained FDA
approval in 1981, despite massive evidence linking it to cancer, particularly, brain cancer.  
Stevia, on the other hand, which is a plant that has been used continually by Paraguayans
for over 1500 years and which has never been associated with ill effects has yet to receive
GRAS (Generally Recognized as Safe) status by the FDA.  In 1991, at the request of an
anonymous complaint, the FDA classified stevia as an "unsafe food additive."  The FDA's
official reason for this decision was "toxicological information on stevia is inadequate to
demonstrate its safety."  Not only did this ruling violate the FDA's own guidelines under
which a natural substance used prior to 1958 with no reported adverse effects should be
generally recognized as safe, but it clearly illustrates the double standard used for natural
substances versus patentable synthetic ones like aspartame where even when extensive
toxciological information demonstrated the chemicals UNSAFETY, approval is nonetheless
granted.

If one still is not convinced that the FDA would approve an unsafe chemical for human
consumption, consider that the fact that every year over 100,000 Americans die from "non-
error" or correctly prescribed drugs - every one of which has received the FDA's explicit
approval. (JAMA April 15, 1998;279(15):1200-5)

So, if  Splenda is not a viable alternative to sugar, what can we
use instead?

When one uncouples the experience of "sweetness" from caloric content, the body becomes
confused because it does not receive nourishment and therefore will not attain satiety - this,
in turn, leads to overindulgence.  Indeed, new studies have shown exactly this: those who
consume synthetic sweeteners are more prone to obesity.  What this means is that when we
ingest something sweet, it should also have caloric and nutritional content. Anything less
than this equation is a recipe for failure and ill health.
Thankfully Nature provides us with a veritable cornucopia of healthy sweeteners: fructose,
honey, agave syrup, stevia, xylitol, erythritol, and dehydrated organic cane juice, all of which
are available at your local health food store.  Next time that sweet tooth calls, remember not
to succumb to advertising hype which would convert poisonous chemicals into "magical" no-
calorie sweeteners.  Use both common sense and a sense of moderation, and your body will
thank you.